首頁 > 生物活性小分子 > Cell Cycle/DNA Damage > DNA Alkylator/Crosslinker
    產品編號 產品名稱 CAS No.
    DC10611 Trabectedin

    Trabectedin (Ecteinascidin-743 or ET-743)是海洋來源的抗癌劑。

    114899-77-3
    DC2099 Cisplatin

    Cisplatin (CDDP) 是一種抗腫瘤的化療劑,它與 DNA 交聯引起癌細胞中 DNA 損傷。Cisplatin 可激活鐵死亡 (ferroptosis) 并誘導自噬 (autophagy)。

    15663-27-1
    DC7689 Evofosfamide(TH-302)

    Evofosfamide (TH-302) 是一種缺氧 (hypoxia) 激活前藥,缺氧 (N2) 和常氧 (21% O2) 環境下,IC50 分別為 10 μM 和 1000 μM。

    918633-87-1
    DC4182 Temozolomide

    Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.

    85622-93-1
    DC8935 Mitomycin C

    Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.

    1950-7-7
    DC9013 Cyclophosphamide

    Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

    50-18-0
    DC9095 Carboplatin

    Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.

    41575-94-4
    DC9298 thiotepa

    N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.

    52-24-4
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