Sapacitabine 是口服可用的核苷類似物前體藥物，與阿糖胞苷結構上相關。

Cisplatin (CDDP) 是一種抗腫瘤的化療劑，它與 DNA 交聯引起癌細胞中 DNA 損傷。Cisplatin 可激活鐵死亡 (ferroptosis) 并誘導自噬 (autophagy)。

Vinorelbine ditartrate 是一種抗有絲分裂劑，能夠抑制 Hela 細胞的增殖，IC50值為 1.25 nM。

Aprepitant (MK-0869) 是選擇性和高親和力的神經激肽1受體拮抗劑，Kd 值為86 pM。

Ombrabulin (AVE8062) 是 CA-4 磷酸酯的衍生物，選擇性破壞內皮細胞的微管蛋白細胞骨架，具有抗血管作用。

Voreloxin (SNS-595; Vosaroxin; AG 7352) 是一種新創的拓撲異構酶 II (topoisomerase II) 抑制劑，能夠誘導 DNA 雙鏈斷裂，阻滯 G2 期，最終細胞凋亡。

Idarubicin hydrochloride是一種蒽環類抗白血病藥物。 它抑制 拓撲異構酶II，干擾DNA復制和RNA轉錄。

Pemetrexed disodium (LY231514 disodium) 是一種葉酸拮抗劑 (antifolate)。Pemetrexed disodium (LY231514 disodium) 的五谷氨酸抑制胸苷酸合成酶 (TS)，二氫葉酸還原酶 (DHFR) 和甘氨酰胺核苷酸甲酰轉移酶 (GARFT)的Ki 分別為 1.3 nM，7.2 nM 和 65 nM。

Pralatrexate(Folotyn)是葉酸類似物，對一些細胞株的 IC50< 300 nM。

Betulinic acid 是一種天然的五環三萜類化合物，為真核細胞拓撲異構酶 I (topoisomerase I) 的抑制劑，IC50 值為 5 μM，具有抗炎，抗瘧疾，抗艾滋病和抗腫瘤等活性。Betulinic acid 也是一種新的 NF-kB 的激動劑。

Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.

Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.

Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.

N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.

5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t