| Cas No.: | 474645-27-7 |
| 名稱: | (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1R,2R)-1-Hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxohe;[3H]-Vedotin;MMAE;MMAE（Monomethyl Auristain E）;MONOMETHYL AURISTATIN E;Vedotin;N-Methyl-L-valyl |
| 別名: | MMAE, SGD-1010 |
| SMILES: | CN[C@H](C(N[C@H](C(N(C([C@@H](CC(N1CCC[C@H]1[C@@H]([C@H](C(N[C@@H]([C@H](C1C=CC=CC=1)O)C)=O)C)OC)=O)OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C |
| 分子式: | C39H67N5O7 |
| 分子量: | 717.97859120369 |
| 純度: | |
| 保存條件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | Monomethyl auristatin E (MMAE, vedotin) is a very potent anti-mitotic agent that inhibits cell division by blocking the polymerisation of tubulin. Because of its super toxicity, it cannot be used as a drug itself. In recent cancer therapy developm |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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