Wnt-C59

    產品編號: DC7340 Featured
    Wnt-C59
    結構式
    1243243-89-1
    此產品僅供科研所需,我們不出售給病人
    ?我們將匹配市場上最好的價格給您
    Email:order@dcbio.cn
    免費咨詢電話:4008862077
    我們的合作伙伴:
    • 20
    • 19
    • 18
    • 17
    • 16
    • 15
    • 14
    • 12
    • 11
    • 10
    • 9
    • 8
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    中國地區超過5000個高品質化合物庫存
    應用領域
    Wnt-C59 (C59)是高效可口服的 PORCN 抑制劑,IC50 為 74 pM。
    Cas No.: 1243243-89-1
    名稱: 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide
    別名: Wnt C59; C59;WntC59
    SMILES: CC1=NC=CC(=C1)C2=CC=C(C=C2)CC(=O)NC3=CC=C(C=C3)C4=CN=CC=C4
    分子式: C25H21N3O
    分子量: 379.45
    純度:
    保存條件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
    Description:
    In Vivo:
    In Vitro:
    References: Wnt-C59 (C59) is claimed to inhibit PORCN enzyme activity at nanomolar concentrations. Wnt-C59 (10 nM) blocks the palmitoylation-dependent Wnt–WLS interaction in HeLa cells transfected with either WNT3A-V5 or WNT8A-V5 plasmids. Wnt-C59 (100 nM) prevents i
    Kinase Assay:
    Cell Assay:
    Animal Administration:
    References:
    MSDS
    COA
    LOT NO. DOWNLOAD
    2018-0101
    產品編號 產品名稱 應用領域
    DC12654 PLX8394 PLX8394 是一種有效的,選擇性的 BRaf 抑制劑,抑制 BRAFV600E 活性的 IC50 值約為 5 nM。
    DC9743 CB1954(Tretazicar) CB1954(Tretazicar) in stock,price: 350 USD/100mg. CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.It can
    DC26175 NLX-101(F-15599) NLX-101(F-15599) is a novel compound that activates serotonin 5-HT1A receptors with exceptional selectivity, having over 1000-fold higher affinity for this target over other receptors.
    DC26173 YM-53601 YM-53601 is a squalene synthase inhibitor (IC50s = 79 and 90 nM in HepG2 cells and rat liver microsomes, respectively).
    DC26160 Ethosalamide Etosalamide, also known as Ethosalamide, is an antipyretic and analgesics agent.
    DC26155 Sulfaphenazole Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Kis = 63 and 29 μM for CYP2C8 and CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19).
    DC26151 Naloxone (hydrochloride) Naloxone is an opioid inverse agonist drug used to counter the effects of opiate overdose.
    DC26139 2-(5-Chloro-1H-indol-2-yl)acetic acid 2-(5-Chloro-1H-indol-2-yl)acetic acid|CAS 720000-48-6
    DC12542 GOT1 inhibitor 2c GOT1抑制劑2c是谷氨酸草酰乙酸轉氨酶1(GOT1)的一流的非共價抑制劑,IC50為8.2μM。
    DC12541 iGOT1-01 iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.
    宝贝你的奶头好紧好大_宝贝你的小缝好紧好滑_宝贝你的胸好大好想吃